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Infections of Pregnancy

From Mediwikis

Rubella

This RNA virus is often (50%) asymptomatic, but may present with:

  • Macular rash
  • Lympadenopathy

The vaccine is live and potentially teratogenic and should not be given during pregnancy.

Complications

  • Cataracts
  • Deafness
  • Cardiac lesions

Cytomegalovirus

This virus often causes congenital malformation.

Symptoms- mild

  • Raised temperature
  • Lympadenopathy
  • Sore throat, rashes

Infection often comes from toddlers urine- avoid contact during pregnancy

Toxoplasmosis

Similar to glandular fever

  • Fever
  • Rash

Investigate- lab antibodies for IgG, IgM. Manage with Spiramycin

Listeria

Symptoms

  • Fever/ Shivering
  • Myalgia
  • Headache
  • Sore throat

Can lead to miscarriage/ stillbirth (20%)

  • Culture blood, CSF, meconium, placenta
  • Treat with ampicillin, gentamycin

Varicella Zoster

If mother develops VZ late

  • Delivery after 7 days
  • Give VZIG to neonate
  • If neonate develops chicken pox, treat with aciclovir

If earlier contact, give VZIG and monitor

  • If chickenpox develops, give aciclovir and monitor closely

Infection in first trimester can lead to fetal varicella syndrome

  • Various congenital deformities

Chlamydia trachomatis

High risk of ectopic pregnancy. 30% of infected mothers have affected babies

  • Low birthweight
  • PPROM
  • Conjuntivitis

Cleanse eye and give erythromycin

Gonococcal conjunctivitis

Symptoms

  • Purulent discharge
  • Lid swelling
  • Corneal hazing/ rupture

50% have concurrent chlamydia.

Treat with cefotaxime and chloramphenicol eye drops.